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pentobarbital will lower the extent or influence of solifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will reduce the extent or influence of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will lessen the extent or result of parecoxib